McGovern DJ, Root DH. (2019). Ventral pallidum: a promising target for addiction intervention. Neuropsychopharmacology, in press.

Phillips AG, McGovern DJ, Lee S, Ro K, Huynh DT, Elvig SK, Fegan KN, Root DH. (2019) Oral prescription opioid-seeking behavior in male and female mice. Addiction Biology e12828. Pubmed

Root DH, Zhang S, Barker DJ, Miranda-Barrientos J, Liu B, Wang H-L, Morales M. (2018b). Selective brain distribution and distinctive synaptic architecture of dual glutamatergic-GABAergic neurons. Cell Reports, 23(12):3465-3479 Pubmed


Root DH, Estrin DJ, Morales M. (2018a). Aversion or salience signaling by ventral tegmental area glutamate neurons. iScience, 2:51-62 Pubmed


Barker DJ, Miranda-Barrientos J, Zhang S, Root DH, Wang HL, Liu B, Calipari ES, Morales M. (2017). Lateral Preoptic Control of the Lateral Habenula through Convergent Glutamate and GABA Transmission. Cell Reports, 21(7): 1757-1769 Pubmed

·         NIDA “Featured” Paper – April 2018


Zahm DS & Root DH. (2017). Review of the cytology and connections of the lateral habenula, an avatar of adaptive behaving. Pharmacology, Biochemistry and Behavior, 162:3-21. Pubmed


Root DH, Wang HL, Liu B, Barker DJ, Mod L, Szocsics P, Silva AC, Magloczky Z, Morales M. (2016). Glutamate neurons are intermixed with midbrain dopamine neurons in nonhuman primates and humans. Scientific Reports, 6:30615. Pubmed

·         NIDA “Featured” Paper – December 2016


Barker DJ, Root DH, Zhang S, Morales M. (2016). Multiplexed Neurochemical Signaling in the Ventral Tegmental Area : Glutamatergic, GABAergic, and Dopaminergic Partnerships. Journal of Chemical Neuroanatomy, 73:33-42. Pubmed

·         NIDA “Reviews to Read” – July 2016


Barker DJ, Striano BM, Coffey KC, Root DH, Pawlak AP, Kim OA, Kulik J, Fabbricatore AT, West MO. (2015).  Sensitivity to self-administered cocaine within the lateral preoptic-rostral lateral hypothalamic continuum. Brain Structure & Function, 220(3):1841-1854. Pubmed


Root DH, Zaborszky L, Melendez RI, Napier TC. (2015b). The ventral pallidum: Subregion-specific functional anatomy and roles in motivated behaviors. Progress in Neurobiology, 130:29-70. Pubmed


Root DH, Hoffman AF, Good CH, Zhang S, Gigante ED, Lupica CR, Morales M. (2015a). Norepinephrine activates dopamine D4 receptors in the rat lateral habenula. Journal of Neuroscience, 35(8):3460-3469. Pubmed

·         NIDA “Featured” Paper – August 2015


Root DH, Mejias-Aponte CA, Zhang S, Wang HL, Hoffman AF, Lupica CR, Morales M. (2014b). Single mesohabenular axons release both glutamate and GABA. Nature Neuroscience 17(11):1429-1622. Pubmed

·         NIDA “Hot” Paper – November 2014

·         Nature Neuroscience Featured Paper

·         Research Highlight, Yates D (2014) Nature Neuroscience Reviews 15:700-701

·         News and Views, Uchida N (2014) Nature Neuroscience 17:1432-1434


Root DH, Mejias-Aponte CA, Qi J, Morales M. (2014a). Role of glutamatergic projections from ventral tegmental area to lateral habenula in aversive conditioning. Journal of Neuroscience, 34(42):13906-13910. Pubmed


Striano BM, Barker DJ, Pawlak AP, Root DH, Fabbricatore AT, Coffey KC, Stamos JP, West MO. (2014). Olfactory tubercle neurons exhibit slow-phasic firing patterns during cocaine self-administration. Synapse, 68(7):321-323. Pubmed


Morales M & Root DH. (2014). Glutamate neurons within the midbrain dopamine regions. Neuroscience 282:60-68. Pubmed


Root DH. (2013b). The ventromedial ventral pallidum subregion is necessary for outcome-specific Pavlovian-Instrumental Transfer. Journal of Neuroscience, 33(48):18707-18709. Pubmed


Barker DJ, Simmons SJ, Servilio LC, Bercovicz D, Ma S, Root DH, Pawlak AP, West MO. (2014). Ultrasonic Vocalizations: evidence for an affective opponent process during cocaine self-administration. Psychopharmacology, 231(5):909-918. Pubmed

·         Featured in The Daily Record, The Examiner, RutgersNews


Coffey KR, Diamond A, Barker DJ, Ma S, Root DH, West MO. (2014). A Procedure for Implanting Organized Arrays of Microwires for Single-Unit Recordings in Awake, Behaving Animals, Journal of Visualized Experiments, 84:e51004. Pubmed


Barker DJ, Bercovicz D, Servilio LC, Simmons SJ, Ma S, Root DH, Pawlak AP, West MO. (2014). Rat Ultrasonic Vocalizations Demonstrate that the Motivation to Contextually Reinstate Drug-Seeking Behavior does not Necessarily Involve a Hedonic Response. Addiction Biology, 19(5):781-790. Pubmed


Ma S, Pawlak AP, Cho J, Root DH, Barker DJ, West MO. (2013). Amphetamine’s dose-dependent effects on dorsolateral striatum sensorimotor neuron firing. Behavioural Brain Research, 244:152-161. Pubmed


Coffey KR, Barker DJ, Ma S, Root DH, Martinez L, Horvitz JC, West MO (2013). Effects of Varying Reinforcement Probability on Pavlovian Approach Behavior and Ultrasonic Vocalizations in Rats. Behavioural Brain Research, 237:256-262. Pubmed


Root DH, Ma S, Barker DJ, Megehee L, Striano BM, Ralston CM, Fabbricatore AT, West MO. (2013a). Differential roles of ventral pallidum subregions during cocaine self-administration behaviors. J Comp Neurol, 521(3):558-588. Pubmed


Root DH, Fabbricatore AT, Pawlak AP, Barker DJ, Ma S, West MO. (2012). Slow phasic and tonic activity of ventral pallidal neurons during cocaine self-administration. Synapse, 66(2):106-127. Pubmed


McGinty VB, Hayden BY, Heilbronner ST, Dumont EC, Graves SM, Mirrione MM, du Hoffman J, Sartor GC, Espana RA, Millan EZ, Difeliceantonio AG, Marchant NJ, Napier, TC, Root DH, Borgland SL, Treadway MT, Floresco SB, McGinty JF, Haber S. (2011). The Reward Circuit: Emerging, Reemerging, and Forgotten Brain Areas: Notes from the 2010 Motivational and Neural Networks Conference. Behavioural Brain Research, 225(1):348-357. Pubmed


Root DH, Barker DJ, Ma S, Coffee KR, West MO. (2011). Evidence for skilled cocaine self-administration in rats. Psychopharmacology, 217(1):91-100. Pubmed


Barker DJ, Root DH, Ma S, Jha S, Megehee L, Pawlak AP, West MO. (2010). Dose dependent differences in short ultrasonic vocalizations emitted by rats during cocaine self-administration. Psychopharmacology, 211:435-442. Pubmed


Root DH, Tang CC, Ma S, Pawlak AP, West MO. (2010b). Absence of cue-evoked firing in rat dorsolateral striatum neurons. Behavioural Brain Research, 211(1):23-32. Pubmed


Root DH, Fabbricatore AT, Ma S, Barker DJ, West MO. (2010a). Rapid phasic activity of ventral pallidal neurons during cocaine self-administration. Synapse, 64(9):704-713. Pubmed

·         Faculty of 1000 Biology Comment, 23 Apr 2010

Tang CC, Root DH, Duke DC, Zhu Y, Teixeria K, Ma S, Barker DJ, West MO. (2009). Decreased firing of striatal neurons related to licking during acquisition and overtraining of a licking task. Journal of Neuroscience, 29(44):13952-13961. Pubmed


Root DH, Fabbricatore AT, Barker DJ, Ma S, Pawlak AP, West MO. (2009b). Evidence for habitual and goal-directed behavior following devaluation of cocaine: a multifaceted interpretation of relapse. PLoS One, 4(9):e7170. Pubmed


Root DH, Barker DJ, Ma S. (2009a). Duality of salience in dopamine neurons. Proceedings of the National Academy of Sciences, 106(12):E84. Pubmed


Silvestri AJ & Root DH. (2008). Effects of REM Deprivation and an NMDA Agonist on the Extinction of Conditioned Fear. Physiology & Behavior, 93:274-281. Pubmed