New manuscript: Salience signaling and stimulus scaling of ventral tegmental area glutamate neuron subtypes

Congratulations to Dillon, Alysa, Annie, and team on the new manuscript entitled Salience signaling and stimulus scaling of ventral tegmental area glutamate neuron subtypes.

VTA glutamate neurons are molecularly heterogeneous but whether this molecular heterogeneity extends to behavioral function is unclear. Dillon and colleagues show that VTA glutamate neuron subtypes differentially signal the value of rewarding experiences, the value of aversive experiences, and behavioral preferences. They also highlight the unique potential signaling of salience by neurons that co-transmit glutamate and GABA. Thanks to all co-authors and collaborators!

Pre-print posted here

Root lab at SfN

Please come chat with us on some of our newest research:

Sunday afternoon KK7 Dr. Dillon McGovern will present his research on VTA circuits and cell-types mediating the consequences of uncontrollable stress

Tuesday morning SS21 Emily Prevost will present her research on VTA mu opioid receptor cell-types and fentanyl reward/aversion